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The exact mechanisms that are preventing GLP-1 drugs from having an effect still need to be investigated

A medical consultation is required to assess suitability before treatment can be initiated

In addition, NTS receives descending projections from forebrain limbic stress-excitatory regions, such as the prefrontal cortex and central nucleus of amygdala (CeA) [20-23], indicating possible involvement of the NTS in processing emotional and cognitive stress responses

Herein, we highlight the potential benefits of GLP-1RAs on CV parameters observed in recent CV outcomes trials and further discuss clinical application of GLP-1RAs in CV medicine

The European Medicines Agencys Pharmacovigilance Risk Assessment Committee also concluded that NAION should be listed as a very rare side effect of semaglutide medications after reviewing clinical trials, post-marketing surveillance, non-clinical data, and published medical literature

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