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Setting up a laboratory in a prefab on the roof of some old buildings at the back of the Royal Free Hospital in 1960, Samols persuaded Vincent Marks (figure 12), a junior doctor with an interest in carbohydrate metabolism, to help him demonstrate the clinical use of RIA

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Zepbound was approved in 2023

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An in vitro study in hCAECs found that exenatide decreased inflammation by reducing activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B), adhesion molecules intracellular adhesion molecules (ICAM) and vascular cell adhesion molecules (VCAM), but not P-selectin (Scisciola et al., 2020)

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