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The blood work tells another, often more important one

One observed a positive association between liraglutide use at 12 weeks and improved MMSE in 47 adults with T2DM, which correlated with increased task (verbal fluency)-based activation of the dorso-lateral prefrontal and orbitofrontal cortex, while several other cognitive tests were not affected 45

It's not always true that the doctor has complete control to prescribe off-label, but I think it's a reasonable way to think about it

J Biol Chem 266: 2897-2902, 1991

[DOI] [PubMed] [Google Scholar] 14.After the LEADER trial and SUSTAIN-6, how do we explain the cardiovascular benefits of some GLP-1 receptor agonists

In clinical trials, tirzepatide and semaglutide have also been associated with a small but slightly increased risk of gallbladder disease, including gallstones