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Moreover, in a recent large cardiovascular outcomes trial (SURPASS-CVOT), numerically higher proportions of participants taking tirzepatide (15 mg weekly) reported nausea, vomiting, and diarrhea compared with those taking the selective GLP-1RA dulaglutide (1.5 mg weekly) (25)

This dual-action approach engages additional metabolic pathways that single-receptor medications cannot reach

They can monitor heart rate, blood pressure, growth in children, and overall health to catch any serious side effects early

[DOI] [PubMed] [Google Scholar] 85

W., & Boxer, R
