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[1] [2] Semaglutide mimics the action of the naturally occurring hormone GLP-1, which is released from the intestine after eating

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Clinical trials show that many people notice appetite reduction within weeks, but responses vary considerably

Patients with baseline hypertension tend to experience more substantial absolute reductions than normotensive individuals, though percentage improvements remain comparable across groups

doi: 10.1210/en.2016-1038

Retatrutide, also known as LY3437943, is an investigational once-weekly injectable medication developed by Eli Lilly