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Description
The conventional understanding of Alzheimer's disease frames it primarily as a problem of protein accumulation: amyloid plaques building up between neurons, tau tangles forming within them, and the resulting structural damage driving cognitive decline

The new label includes references to some of those postmarketing risks, including intestinal obstruction, [and] severe constipation including fecal impaction. Some patients who took Zepbound have filed lawsuits, accusing Eli Lilly of failing to properly warn them that Zepbound could increase their risk of severe gut problems, including bowel obstructions, pancreatitis, and gastroparesis

In other words, they reduce the exaggerated salience

Each additional milligram produces diminishing returns

GLP-1R-expressing cells were targeted using fluorescently labelled Exendin-4 (Fluorescein-Trp25-exendin-4

Sokol, H., Lavergne-Slove, A., Mikol, J., Sabate, J
