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Description
As discussed below, the development of unimolecular multi-agonists that stimulate GLP-1 receptors and other receptors such as GIP receptors and glucagon receptors (GCGR) can have beneficial effects on metabolism and increase metabolic rate at tolerable doses [57]
The causal link for these conditions is more difficult to prove in the current litigation framework
[DOI] [PubMed] [Google Scholar] 94.Jin T
In addition, treatment with the long-acting GLP-1RA duraglutide restored muscle mass and function in DBA/2J-mdx mice
Tirzepatide showed greater reductions in HbA1c and body weight at week 52, along with a lower risk of hypoglycemia [67]
Lancet 381 , 117124 (2013)
