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Understanding the medication's mechanism of action helps contextualise why certain effects, including potential skin changes, might occur during therapy
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The potential of GLP-1RAs to reduce alcohol consumption in humans was first reported at a scientific conference in 2011.141 An RCT157 evaluated the effect of 26 weeks of once-weekly exenatide treatment on the frequency of heavy drinking days in patients diagnosed with AUD
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If retatrutide follows the typical regulatory pathway, a first approval for obesity could arrive in 2026 or 2027
