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A letter in JCP responding to McIntyre's GLP-1 commentary proposes a -cellcentric view especially for Asian populations where the danger is pancreatic -cell failure

if Orforglipron is successfully commercialized, Chugai will also be entitled to royalties for patent usage.

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Patients with nonalcoholic steatohepatitis (NASH) are at higher risk of progression to advanced stages of fibrosis, cirrhosis, hepatocellular carcinoma and other end-stage liver disease complications