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Weight Loss and Metabolic Benefits Obesity is a major CVD risk factor, and GLP-1 agonists promote significant weight loss (515% of body weight) by reducing appetite, enhancing satiety, and slowing gastric emptying [47]

[DOI] [PubMed] [Google Scholar] 87.Jastreboff AM, et al

Dehydration can lead to acute kidney injury, particularly in patients with pre-existing renal impairment or those taking concurrent medications affecting kidney function

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and Akkermansia spp., effectively moderating the microbial imbalance and colonic inflammation triggered by experimental colitis, alongside preserving the integrity of the mucus barrier (Ke et al., 2021

A hypoglycemia episode was defined as a severe hypoglycemia episode or an episode where a laboratory or a self measured glucose calibrated to plasma was less than 56 mg/dL or where a whole blood glucose was less than 50 mg/dL (i.e., with or without the presence of hypoglycemic symptoms)