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Description
Daily GIP injections led to a decrease in the adipose tissue gene expression levels of pro-inflammatory cytokines, such as Il-1 beta, Il-6, TNF-alpha in wild-type mice, 60 while blood levels of adiponectin, an anti-inflammatory and insulin-sensitizing adipokine, are enhanced

Presented at the Alzheimers Association International Conference (AAIC)

GLP-1RA treatment initiation was the exposure of interest

In the phase II program, tirzepatide was also shown to improve biomarkers for cardiovascular risk and to improve NASH (6365)
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AZ paid $185m to Eccogene, with potential future payments of $1.8bn

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