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doi: 10.1016/j.xphs.2022.01.008 112 SicardJ

A large chain pharmacy, such as CVS or Walgreens, might have negotiated a slightly better cash price than a small, independent corner pharmacy

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This is why the gradual dose escalation schedule prescribed with these medications is important and why skipping doses or restarting at a full dose after a break can cause more significant side effects.

In people with type 2 diabetes, this incretin effect is significantly reduced

The in vitro and preclinical data suggesting direct testicular action have not yet been confirmed in large, well-powered human trials
