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It can affect patients both on a psychological and physical level, with overweight and obese people found to be at risk for diabetes, cardiovascular disease, cancer, and premature death [2]

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Collectively, these studies suggest that central rather than peripheral GLP-1/GLP-1R mediates the alcohol responses

Clin Drug Investig 36(4):313319

Oxyntomodulin, another endogenous ligand of the GLP-1R and the glucagon receptor and allosteric ligands of the GLP-1R have been reported to exhibit some degrees of G-protein bias at the GLP-1R 31,32
