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Cons of Thigh Injections Potential for Slower Absorption : Some users have reported that the thigh may result in slightly slower absorption of the medication compared to the abdomen

Dual incretin receptor activation enhances glucose-dependent insulin response and modulates appetite-regulating pathways

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Additionally, tirzepatide has demonstrated a significant impact on reducing the fasting circulating triglyceride levels [7]

A microdose tirzepatide schedule might use 1 to 2.5 mg weekly instead of the standard 5 to 15 mg range

Do not use in patients with a previous serious hypersensitivity reaction to tirzepatide or any of the excipients in ZEPBOUND [see Contraindications (4) and Adverse Reactions (6.2)]