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[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Jiao Y, Chen X, Liu L, Lu Y, Gao M, Wang Q, et al

A1C Reduction: Rybelsus -1.8% vs Metformin -1.5% Both medications are effective at lowering blood sugar levels, but Rybelsus has a slight edge

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Additionally, physicians employ gradual dose titration strategies starting from low doses and increasing slowly to minimize side effect burden while achieving therapeutic effectiveness

These main effects are indicated in the text and figure legends

Specifically, we tested the TSH receptor (TSHR) and the melatonin receptors MTNR1A and MTNR1B