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Additionally, data on age, sex, and race were collected for all participants
all storage must follow the specific IMP label or trial protocol

Perhaps the best single paper on this topic comes from Oprea and colleagues and was published in the British Journal of Anaesthesia in July 2025

tirzepatide targets GIP and GLP-1

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That delay gives colonic bacteria more substrate to ferment, increasing production of hydrogen, methane, and carbon dioxide