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Researchers are pretty sure that's because GLP-1 drugs are essentially breaking key addiction cycles in the mouse brain

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Oxidative stress is associated with amyloid-- or tau-induced neurotoxicity, which results in impaired synaptic plasticity, neurotransmitter imbalance, and neuronal loss, leading to cognitive impairment (Huang et al., 2016

doi: 10.1016/j.nut.2019.06.003

This supports ATP regeneration during short bursts of intense effort, which translates to better performance in resistance training, faster recovery between sets, and over time, greater stimulus for muscle protein synthesis and retention