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81 It has been hypothesised that insulin moves through the blood-brain barrier into the brain and acts as a neuropeptide positively regulating satiety, olfaction, cognition and memory as well as regulating systemic functions such as hepatic glucose production

Metformin is not FDA-approved for weight loss.

These drugs were initially developed for the treatment and/or management of diabetes, but scientists thought this drug could be a direct cure for obesity as well

Recommended Outcomes of GLP-1 RA in Diabetes & CVD: What are the key opportunities for cardiology practice?Translating GLP-1RA trial outcomes to cardiology practice: Which patients will benefit

Employers and health plans alike must consider strategies, such as leveraging integrated data, to ensure appropriate utilization and prevent unnecessary spend

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