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Study Design We designed this retrospective cohort study to emulate a target trial of GLP-1 RA use compared to an active comparator treatment with dipeptidyl peptidase 4 inhibitors (DPP-4is) for prevention of cirrhosis and related complications in patients with MASLD and diabetes

PMID: 7883856

Outcome studies show that GLP-1 medicines reduce rates of complications associated with T2D and/or obesity, including cardiovascular diseases, metabolic dysfunctionassociated liver diseases, chronic kidney disease, osteoarthritis, and obstructive sleep apnea (Figure 1)

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International claims face additional jurisdictional challenges

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