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In an 8-week study using low-dose liraglutide (0.6 mg/day) in patients with type 2 diabetes no weight or fat loss was produced, but both fasting and postprandial glucose were substantially reduced, but neither fasting nor postprandial insulin (or C-peptide) response was increased [19]

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3.2 Effect of liraglutide on food and water intake, body composition and glycaemia In addition to its insulinotropic action, GLP-1 has also been shown to reduce food intake and slow gastric emptying ( Figure 2A ), attributable to the low circulating levels of leptin ( Figure 2B ), which is consistent with polydipsia, a recognised feature of diabetes ( Figure 2C )