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Description
The decision to use these treatments should involve a comprehensive discussion of individual risk factors, family history, and the balance between metabolic benefits and potential concerns
These may include nausea, decreased appetite, vomiting, constipation, diarrhea, bloating, or abdominal discomfort
Results: Nausea, vomiting, diarrhea, and constipation were the most frequently reported GI adverse events, generally dose-dependent and transient
The substantial weight loss achievedtypically 1015% of body weight with semaglutide 2.4mg as demonstrated in the STEP clinical trialshas raised important questions about body composition changes during treatment
That is roughly double to triple the discontinuation rate seen with semaglutide
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