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Light exposure Ultraviolet light accelerates oxidation of vulnerable amino acid residues in the semaglutide peptide chain
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Injectable semaglutide, particularly Wegovy, may be more effective for weight loss than oral semaglutide, according to clinical trials
Since people choosing to de-escalate their GLP-1 therapy might also be more motivated to adopt behavioral strategies for improving their health, there might be underlying selection bias in the study population
Combining both remains an off-label approach based on mechanistic theory rather than robust trial data
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