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Larger, multicenter studies with longer follow-up periods are needed to validate these findings

The fatigue typically stems from three sources: reduced caloric intake (you are eating less, which means less fuel), GI discomfort (nausea and stomach issues are exhausting), and metabolic adjustment as your body adapts to new hormone signaling patterns

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Because of this prolonged effect, careful titration is especially important

These changes in eating habits help with weight loss and may similarly impact cravings for addictive substances, including alcohol, by dampening the motivation and pleasure derived from alcohol consumption

Should clinicians screen for depression in patients starting GLP1 therapy