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You are trading FDA approval for a lower price
GLP-1, or glucagon-like peptide-1, is a hormone released in the intestines in response to food intake
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Tirzepatide is a GLP-1 receptor agonist too, but it is also a GIP (glucose-dependent insulinotropic polypeptide) receptor agonist

Complete comparison: tirzepatide versus every alternative Numbers tell the story better than paragraphs when comparing this many options
