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However, both visceral and subcutaneous fat play significant but differing roles in systemic inflammation 101 , 102 and it is therefore possible that the improved outcomes are the result of improvements in obesity and T2DM rather than a direct effect of the GLP-1RA

doi: 10.1089/acm.2020.0331

A 10-week study with a very low energy diet shows that weight loss induces adverse gut hormonal changes that potentially affect weight regain and persist [46]

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