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GLP-1 receptor agonist medications that help: Reduce appetite Improve how the body responds to insulin Support weight loss efforts Maintain steady blood sugar levels While these medications work wonders for many, others might not see the full benefits and can experience digestive and other bodily discomforts

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On GLP-1s

Herein, we show that broad-spectrum antibiotic cocktail (ABX)-treated mice displayed hypolocomotion and elevated levels of the gut hormone glucagon-like peptide-1 (GLP-1)

To counter dipeptidyl peptidase-4-mediated cleavage, our method strategically incorporates noncanonical amino acid ornithine at position 8 utilizing microbial modification enzyme OspR in vivo