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According to the Pharmacotherapeutic Compass, both medicines are indicated as an adjunct to a calorie-restricted diet and increased physical activity in adults with a BMI of 30 or higher, or 27 or higher in the presence of weight-related comorbidities

Both tirzepatide and semaglutide are FDA-approved, have support from more long-term data, and are already used in real-life settings

Are polyunsaturated fatty acids implicated in histaminergic dysregulation in bipolar disorder?: an hypothesis

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The incretin hormone glucagon-like peptide 1 increases mitral cell excitability by decreasing conductance of a voltage-dependent potassium channel