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They counteract the imbalance between bone production and resorption that is typical in type 2 diabetes by promoting bone formation and enhancing blood supply to bones

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Insulin resistance syndrome Indeed, environmental factors and genetic predispositions play significant roles in the development of insulin resistance syndrome, which is characterized by an increase in adipose tissue mass

19% in placebo arm, p = 0.001), but no improvement in fibrosis (p = 0.24).25 There have also been subsequent safety concerns regarding the use of vitamin E, as data suggest a possible increased risk of overall mortality and higher rates of prostate cancer, though this remains controversial.[26], [27], [28] The insulin sensitiser pioglitazone, a thiazolidinedione, has been well studied and prescribed by some for the treatment of NASH, usually in line with diabetic practice guidelines