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Clinical trial data suggest that gastrointestinal side effects, including any reflux symptoms, typically improve over time as patients develop tolerance to the medication

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This classic paper describes different pathophysiological subgroups in a large number of patients with functional dyspepsia, including delayed emptying and reduced gastric accommodation

This is the same mechanism that causes the initial "water weight" when starting creatine but in the context of GLP-1 therapy, maintaining intracellular hydration is a feature, not a bug

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