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Pancreatitis: Inflammation of the pancreas is a serious condition that has been observed in some people on GLP-1 agonists

For most older adults with obesity, type 2 diabetes, or cardiovascular disease , the benefits are substantial but the potential risks must also be considered: Benefits: cardiovascular protection , significant weight loss , improved glucose control , blood pressure , and inflammation , with a lower risk of hypoglycemia compared to many older therapies

These changes sound important, but they do not make a big difference in how long semaglutide stays in the body

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Some people may experience side effects after taking metformin, with the main symptoms being gastrointestinal distress and, in rare cases, lactic acidosis (Sanchez-Rangel and Inzucchi, 2017)