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This activation, potentially mediated by peripheral nerve signaling or inflammatory factors crossing the BBB, disrupts neural activity and connectivity in anxiety-related circuits, such as the mPFC-amygdala axis

More studies are required to understand whether and how exogenous cannabis administration, as well as different components of the endocannabinoid system, may have direct and/or indirect influences on the GLP-1 system

If you experience new or worsening reflux symptoms after starting Ozempic, this warrants discussion with your GP or diabetes specialist

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Dose and individual sensitivity Semaglutide doses start low and gradually increase because sensitivity varies dramatically between individuals

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