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And if you happen to be one of the 5-10% of users struggling with diarrhea or vomiting on your medication, you'll need to replenish your fluids even more rapidly

Indeed, cyclers warned side effect issues with the oral candidate (CT-996) could limit its competitiveness ( [60] )

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5 Mechanistically, exercise-induced interleukin-6 (IL-6) appears to stimulate GLP-1 secretion from intestinal L-cells and pancreatic -cells in experimental models, which may contribute to improved appetite regulation and insulin secretion during and after exercise

No serious adverse events related to skin sensitivity were documented, and no participants discontinued treatment solely because of this side effect