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Less common but more serious risks include pancreatitis, gallbladder disease, hypoglycemia (when used with insulin/sulfonylureas), kidney injury (with severe dehydration), and retinopathy worsening in patients with pre-existing diabetic retinopathy

This comes from stability data on the FDA-approved formulation of tirzepatide (Mounjaro and Zepbound), which compounding pharmacies use as a reference point for their own formulations

According to the Cleveland Clinic, tirzepatide maintains its potency when stored properly, but only until that crucial expiration date

But for now, we have new options that are safe, appear to reduce complications, and are very effective

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It is the worlds second-best selling prescription medicine, with combined sales of $26bn in 2024 and growing annually at a staggering 40%