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This narrative reviewaims to analyzecurrent findings on the beneficial and adverse ocular effects of GLP-1RAsuse, highlighting studies that elucidate the harmful causes, such as retinal microvascular dysregulation, inflammatory modulation, oxidative stress,osmotic dysregulation from sorbitol accumulation,and metabolic shifts

GLP-1 receptor agonists have absolutely changed how we treat metabolic disease

A Renewed Look at an Old Controversy Ever since GLP-1 receptor agonists (GLP-1 RAs) entered clinical practice for diabetes and obesity, their metabolic benefits have been undeniable

Learn how oral GLP-1 medications work, who's a good candidate, and what to expect from treatment.

Background Despite the effectiveness of glucagon-like peptide-1 agonist (GLP-1A) in the treatment of diabetes, its large molecular weight and high hydrophilicity result in poor cellular permeability, thus limiting its oral bioavailability