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Common contributors include sleep disorders, chronic stress, hormonal imbalances (particularly thyroid dysfunction), nutritional deficiencies (such as vitamin B12 or iron), autoimmune conditions (like multiple sclerosis or lupus), medications, and metabolic disorders including diabetes

Histochem Cell Biol (2019) 151(2):11523

Trends Endocrinol Metab (2017) 28(2):88103

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The activation of the GIP receptor in the arcuate, dorsomedial and paraventricular nuclei of the hypothalamus decreased food intake in obese mice

10.1038/s41398-020-00923-1 72 VallofD.MaccioniP.ColomboG.MandrapaM.JornulfJ
