tirzepatide surpass Matches Dulaglutide in Large CV Outcomes Trial: SURPASS-CVOT SURPASS-CVOT: Tirzepatide Significantly Reduces Major

40 mg vs 20 mg vs 10 mg

When excluding patients who had been diagnosed with diabetic retinopathy in the second sensitivity study, use of once-weekly semaglutide was still independently associated with a higher risk to develop NAION (adjusted HR 226, 95% CI 157 327) in a multivariable model adjusted as in the first sensitivity analysis

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Slowing gastric emptying , so food moves more gradually through the stomach, reducing sharp blood sugar spikes