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GLP1 agonists like Semaglutide, Liraglutide may increase risk of pancreatitis, gastroparesis and bowel obstruction US: Researchers at University of British Columbia have found in a new study that that use of glucagon-like peptide-1 agonists for weight loss compared with use of bupropion-naltrexone was associated with increased risk of pancreatitis, gastroparesis, and bowel obstruction but not biliary disease

Where New Matter Actually Comes From: CIP Trigger Points in FDA Drug Development Why Preclinical Polymorphs and Phase I Formulation Data Drive Most Secondary Patent Filings The FDAs five-stage development pathway discovery, preclinical, Phase I, Phase II, Phase III and post-approval does not generate patentable new matter at uniform rates

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