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Insulin and IGF-1 signaling GLP-1 medications improve insulin sensitivity, which is one of their major metabolic benefits

These fibers slow down the digestion and absorption of nutrients, leading to a more gradual release of glucose into the bloodstream, which in turn stimulates the production of GLP-1

The enterohepatic circulation of bile acids plays a role in the digestion and absorption of fatty foods, promotes the excretion of bile acids, and inhibits the precipitation of cholesterol in bile ( Figure 2 )

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This increases intragastric pressure and can promote reflux of stomach contents into the oesophagus, leading to heartburn and reflux symptoms

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