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Evidence that systemic NAD pools undergo inter-organ redistribution and dynamic turnover [96, 107, 126] supports the view that redox stability reflects flux kinetics rather than static metabolite concentrations

Exclusion of patients of the following cardiovascular diseases was defined as low risk of cardiovascular disease (such as myocardial infarction, heart failure, coronary heart disease, stroke, angina pectoris and other serious cardiovascular disease)

doi: 10.1016/j.physbeh.2011.05.026

Psychiatry 64, 327337

Several large clinical trials have demonstrated that GLP-1 receptor agonists can reduce the risk of cardiovascular events, such as heart attacks and strokes, in people with type 2 diabetes who are at high risk for heart disease

Low blood sugar (hypoglycemia)