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As a researcher at the Danish pharmaceutical company Novo Nordisk, Knudsen and her team realized that regular GLP-1 wouldnt work as a drug
cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic -cells

They are designed to complementnot replacenutrition, physical activity, sleep, and long-term behavior change

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