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Evidence-based guidelines recommend 1.2 to 1.6 grams of protein per kilogram of ideal body weight dailysubstantially higher than standard dietary recommendationsto preserve lean muscle mass, maintain metabolic rate, and optimize body composition

Comparison of acarbose and metformin therapy in newly diagnosed type 2 diabetic patients with overweight and/or obesity

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These findings provide a comprehensive structural framework for developing next-generation anti-obesity drugs based on dual receptor activation mechanisms

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A small percentage of patients report persistent loose stools, which may indicate a need for dose adjustment or dietary modification rather than medication discontinuation