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Before Zepbound Existed: Mounjaro was the only tirzepatide option available from May 2022 until November 2023 when Zepbound received FDA approval for weight loss
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In humans, DPP-4is, including sitagliptin, have demonstrated the ability to decrease systemic inflammatory mediators, including C-reactive protein (CRP) and interleukin-6 (IL-6) and other inflammatory markers in human patients with T2DM in clinical trials [80,81]
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If gaining weight isnt a moral failing, then losing weight doesnt need to be either
