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Some patients are nonresponders to the drugs, while others have a high response, and these distinct responses arise even within individual families

Key advances In the SURMOUNT-1 trial for obesity, adults with overweight or obesity without type 2 diabetes mellitus achieved placebo-subtracted weight loss of up to 20% after 72 weeks of the GLP1GIP receptor co-agonist tirzepatide, with a similar safety profile to high-dose semaglutide 5

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Optimizing GLP1 hormone production through the lens of the gut microbiome
