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Depressed diabetics face a 1.5-fold increased risk of all-cause mortality and a 1.4-fold increased risk of cardiovascular mortality [140]

When interpreted alongside your baseline blood pressure, weight, kidney function, and cardiovascular history, this predisposition data may reveal why certain patients respond robustly while others show minimal changehelping your provider anticipate monitoring needs and dose timing

Potential interactions include insulin secretagogues and insulin, which may increase the likelihood of hypoglycemia, as well as the increased toxicity of ifosfamide

Cardiol Clin (2014) 32(1):2132, vii

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Glucagon like peptide-1 protects b-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop