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Wegovy Semaglutide GLP-1

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Whether the positive impact of GLP-1RAs on hepatic histology is indirect, i.e., through their action on extrahepatic tissues, or whether their action is direct, i.e., through activating GLP-1R on the hepatocytes, is still a controversial issue

Immunofluorescence, Western blot, and RT-qPCR were used in the study

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The primary concern with elevated bilirubin in semaglutide-treated patients is distinguishing benign causes (Gilbert's syndrome, hemolysis) from drug-induced...
