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12, 2026 Nature, Are obesity drugs causing a severe complication
GLP-1 and GIP are incretin hormones that are released during a meal, after the ingestion and absorption of glucose, protein, and fat, and provide one of the physiologic connections between eating and insulin release [20,21]
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During this period, Tirzepatides dual action on GLP-1 and GIP receptors helps regulate appetite and improve the bodys natural response to insulin, allowing for gradual, sustainable fat loss rather than rapid fluctuations

These medications mimic the GLP-1 hormone, helping regulate appetite, digestion, and blood sugar control