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Recurrent Idiopathic Intracranial Hypertension-Related Papilledema After Abrupt Discontinuation of Semaglutide

The anti-inflammatory mechanisms appear to be independent of weight loss or glycemic improvement, suggesting direct immunomodulatory properties

More recently, the FDA has approved select GLP-1 therapies specifically for weight loss, including: Wegovy (semaglutide) Saxenda (liraglutide) Zepbound, a GIP/GLP-1 dual-acting therapy (tirzepatide) How do they work

The bridge program covers three FDA-approved GLP-1 medications when used for chronic weight management: Wegovy (semaglutide injection and tablets), Zepbound (tirzepatide KwikPen), and Foundayo (orforglipron, the first oral GLP-1 pill for weight loss)

2014;348:g2366

Discovery of ecnoglutidea novel, long-acting, cAMP-biased glucagon-like peptide-1 (GLP-1) analog