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The American Association for the Study of Liver Diseases (AASLD) acknowledges the potential role of GLP-1 receptor agonists in managing MASLD, particularly in patients with concurrent type 2 diabetes or obesity
These findings not only establish that the alpha-cell transcriptional heterogeneity translates into subpopulations that are functionally distinct but also suggest that specific alpha-cell subpopulations may differentially respond to and contribute to metabolic dysfunction
