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Many commercial insurers have not yet opted to cover these drugs (Accolade, 2023) or include step therapy or prior authorisation provisions that delay eligibility and access (Wingrove, 2023)

Tirzepatide as an antidiabetic and weight-loss therapy: Clinical and mechanistic insights

Semaglutide should be stopped if a patient experiences sustained increasd heart rate

[DOI] [PubMed] [Google Scholar] Mortensen K, Christensen LL, Holst JJ, Orskov C

Most people notice appetite suppression and early weight changes within 2 to 4 weeks of starting treatment, with more significant weight loss becoming visible after 8 to 12 weeks