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Description
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Metabolism During the initial 24 hours following administration of a single [ 3H]-liraglutide dose to healthy subjects, the major component in plasma was intact liraglutide
By 12 months, they had lost an average of 17.4% of their body weight

The pill penalty the IRAs disparate treatment of small molecules (9-year negotiation clock) versus biologics (13-year clock) is not a minor policy distinction

JAMA 2021;325:1403-13.ArticlePubMed 32

Found handles the prior authorization process for members, reducing the administrative burden
